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03 March 2006

Rapid Detection of Community-Acquired MRSA Infection (An Emerging Cause of Necrotising Faciitus)

Recent reports of community-acquired MRSA causing necrotising faciitus have highlighted the potential danger of resistant Staphylococcus aureus strains to otherwise healthy individuals in the community. Microbiology experts, Oxoid Limited, provide a wide range of products for the fast and effective growth and detection of MRSA strains. These methods are invaluable in the rapid diagnosis and prompt treatment of MRSA infections.

Necrotising faciitus, sometimes referred to as ‘flesh-eating disease’, is a life-threatening infection requiring urgent surgical and medical therapy. It is most often caused by Group A streptococci, Clostridium perfringens or a mixture of aerobic and anaerobic organisms. Historically, Staph. aureus rarely causes necrotising faciitus, however an alarming number of cases caused by community-acquired (CA) MRSA have recently been reported at a medical centre in the United States.

MRSA is no longer a problem confined to hospitals. CA-MRSA is becoming more common around the world. The Center for Disease Control and Prevention in the United States estimates that 12% of clinical MRSA infections are community acquired (varying by geographic region and population). In the UK, 100 cases of CA-MRSA have been reported in the last 3 years and one patient has died. Doctors and microbiologists should be aware of the increasing incidence of CA-MRSA around the world and the possible involvement of these strains in life-threatening infections, such as necrotising faciitus.

Oxoid products for the detection and isolation of MRSA strains provide valuable confirmation of MRSA, quickly, conveniently and reliably. These include a range of suitable culture media, such as Oxoid ORSAB selective medium (Product Code: CM1008 and SR0195) and Oxoid Chromogenic MRSA Agar (Product Code: PO1091A) for the detection of MRSA from routine swab samples, and a full range of products for antimicrobial susceptibility testing. In addition, the Oxoid PBP2′ latex agglutination test (Product Code: DR0900A) detects MRSA specific antigen in suspect colonies within just a few minutes, providing rapid confirmation and allowing prompt initiation of appropriate treatment and control measures. This test has already proven to be invaluable in many hospitals around the world, providing results a day earlier than traditional methods.

For further information about Oxoid products for the detection of MRSA, please telephone 01256 841144, email val.kane@oxoid.com.